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13 April 2022


Estradiol is one of three estrogen hormones produced naturally in the body. Although men and women are abstract, women have much higher hormone levels than men. Estradiol controls the distribution of fat in women's bodies. Men with less. The purpose of this hormone is to protect the reproductive system. Increased levels of estradiol during the menstrual cycle cause the egg to mature and release, and the uterine lining thickens to allow the fertilized egg to be transported. It is a hormone made from eggs. As women get older, they fall and more and more menopause. In men, this hormone is beneficial for bones, helping to produce nitric oxide and brain function.

What are the problems with estradiol?

In women, too many subjects are associated with constipation, loss of sexual desire, and depression. If levels are excessively high, they can increase the risk of uterine and breast cancer and cardiovascular disease. Women with high levels of estradiol may experience weight gain and menstrual problems. For men, this can lead to the development of female traps and loss of sexual function or muscle tone. If the body does not have enough estradiol, bone growth and development slows down and osteoporosis (bone weakness) can develop in adults. Girls can delay puberty with low levels of estradiol. Mood changes are also linked to low estradiol levels.

What is the relationship between estradiol and menopause?

In menopausal women, the effects of estradiol are clearly visible. During this process, as the ovaries are no longer produced, women naturally have lower levels of estradiol, causing their menstrual cycles to stop. This change often causes mood swings, vaginal dryness, hot pressure, and nighttime sweetness. These are the symptoms of menopause. Also, low estradiol osteoporosis which can lead to osteoporosis.

Should menopausal women undergo hormone replacement?

Until recently, most women who had entered menopause were on hormone replacement therapy to help reduce their menopausal symptoms, and were often using estradiol. Although menopausal symptoms may improve, recent research has revealed that this treatment increases the risk of blood clots, heart disease, stroke and breast cancer. But age, lifestyle, and medical conditions also play a role. The best method is to implement a personalized treatment plan for gynecology and obstetrics.

How is estradiol level measured?

It can be measured with a blood test. The alias is E2. If the doctor suspects a problem with a high or low level of E2, they may order this test. These problems can be listed as follows:

  • menstrual problems
  • Ovarian tumors
  • Sports as a man
  • Menopause symptoms
  • breast cancer

During puberty, this test can also be done to diagnose the early stages of puberty. E2, FSH and LH values, TSH/FT4 and prolactin values ​​can also be evaluated.

What should the estradiol level be?

Results are given in picograms per milliliter (PG/mL). Normal Levels for Estradiol:

  • 30 to 400 PG/mL for premenopausal women
  • 0 to 30 PG/ml for postmenopausal women
  • 10 - 50 PG/mL for men

If results are lower, it could mean low estrogen due to an error of variability. This is also called early menopause. or rapid weight loss or anorexia. If the results are higher, it may suggest the ovaries, testicular, or adrenal glands for a tumor.

What is the importance of IVF E2?

In IVF treatment, E2 is expected to be 50 PG/ml on two and three days of the menstrual period. If this value is above 50, it is likely that the egg reserve is bad.

What affects estradiol levels?

Certain factors can affect estradiol levels. Some drugs can be effective at these levels.

Medications that can affect estradiol levels include:

  • birth control pills
  • estrogen therapy
  • Glucocorticoids
  • Phenotides are used to treat schizophrenia and other mental disorders
  • Antibiotic tetracycline and amphylline

Estradiol levels can differ throughout the day and throughout a woman's period. As a result, the doctor may ask you to perform a blood test at a certain time of the day or at a certain time of your cycle. Conditions that can affect estradiol levels may include:

  • Anemia
  • high blood pressure
  • kidney disease
  • less liver function

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