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Embryo Donation

With the union of a sperm and an egg, the adventure of pregnancy will begin. If sperm or eggs are not produced, it will not be possible to have a child. It has developed an embryo donation procedure especially for couples who cannot become parents with their own reproductive cells, cannot produce quality embryos due to advanced age, or do not want to transfer their genetic patients to their babies. Embryo donation is the most suitable method for solving some infertility problems.

What is embryo donation?
Embryo donation is an assisted reproductive technique that takes place by transferring unused quality embryos produced by a couple's sperm and eggs to another individual. The transferred embryos are obtained from couples who are undergoing IVF treatment and do not want to have more babies. Embryo donation is used when both sperm and egg cells are not sufficient for pregnancy.
In vitro fertilization cycles usually create a large amount of embryos and can be stored by freezing, considering the failure of the treatment. However, for couples who have completed their families, embryos can be destroyed by thawing or donated to give someone else the potential to become pregnant.

Who is embryo donation applied to?
Before embryo donation was developed, for some individuals the only way to become parents was through the adoption procedure. Although embryo donation is accepted as another method of adoption, pregnancy and childbirth experience can be gained to women suffering from infertility problems.

Embryo donation;

Having long-term infertility problems, Having recurrent IVF failures, Not wanting to transfer genetic diseases to the baby,
It can be applied to women who cannot produce good quality embryos in order to create a pregnancy, who can continue the pregnancy and who do not have a disability to give birth.
What are the types of embryo donation?
The first decision to be made before starting the embryo donation procedure is whether there will be any communication between the recipient and the donor. The type of embryo donation is determined by this preference.

In this type of donation, the identity information of the donor and recipient couple is kept completely confidential. Depending on the agreement between the parties, medical records can be accessed without knowing the identity information.

Known donation:
In the known donation method, embryo donors are selected by the recipient. It requires greater involvement from both donors and recipients, and the parties clearly know each other. This option is ideal for donors who want to be involved in the selection of recipients while also establishing a potential relationship with the recipient family.

Half-open donation:
Donors can set criteria for recipients, match but remain anonymous. It is suitable for embryo donors who want to specify more detailed or specific criteria.

How is embryo donation done?

Consultation: Couples or individuals who want to become parents with embryo donation should first have a detailed discussion with a specialist doctor. The patient's medical history is reviewed and eligibility for the donor embryo program is determined. Several appointments may be required to understand the stages of the process, the cost of the procedure, the patient's expectations and preferences in detail.
Screening: The buyer will need to undergo a physical and psychological screening. A comprehensive medical history of both parties is requested, including blood type and Rh factor. Sexually transmitted diseases such as HIV, hepatitis, chlamydia, and syphilis should also be tested. Upon completion, the patient is given a list of available embryos; The primary and secondary donor is given time to decide.
Matching: A detailed study is carried out to ensure an exact match between the recipient and the donor. After the donor is selected, treatment planning is made.
Preparation of the recipient: A drug protocol is prepared in order to regulate the menstrual cycle of the recipient and to make the uterus suitable for pregnancy. It is aimed to suppress the ovaries and enlarge the inner lining of the uterus. While taking estrogen supplementation, the woman should attend control appointments, the thickness of the inner wall of the uterus and hormone levels should be monitored. Progesterone supplement will also be given when the inner wall of the uterus is ready.
Embryo transfer: The prepared embryos are dissolved and made ready for transfer. Embryo transfer is a simple and painless procedure. Embryos in a thin catheter are delivered to the uterus under ultrasound guidance and released there. A pregnancy test can be applied two weeks later to the recipient woman who needs to avoid heavy physical activities for a while. If a positive result is obtained, pregnancy follow-up will begin and progesterone – estrogen supplementation will be continued until the 10th week of pregnancy.

Who can be an embryo donor?
All health centers and recipients are very sensitive in the selection of donor embryos. Individuals who will be embryo donors need to go through all health screenings and be knowledgeable about legal processes. The criteria that an acceptable donor and embryo should have are as follows:

Donors are preferably requested to have completed their own family.
The egg that makes up the donor embryo must be obtained from a woman younger than 35 years of age.
The detailed medical history and biological origin of the donor couple should be known.
Detailed screenings should be done to rule out the possibility of an inherited condition or contagious infection.
Legal obligations and agreements between the parties must be agreed in full detail.

What is the success rate for those who have embryo donation?

The success rate of the embryo donation procedure varies depending on the quality of the embryos at the time of freezing, the age of the woman providing the egg, and the number of embryos transferred. The chance of implantation is expected to be higher as donor embryos must successfully pass genetic diagnostic tests prior to transfer.
It is also very important that the recipient is healthy before receiving the donor embryos. All medical problems that may reduce success should be screened and treated. Considering all these criteria, it is stated that the pregnancy rate after embryo donation is approximately 40%.

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